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Prof. Dr. med. Hans-Christoph Ludwig 

Kinderneurochirurgie  -  Oberarzt

Robert-Koch-Straße 40
37075 Göttingen
0551 398741
0551 398794
E-Mail

 
 

Aus- und Weiterbildung

Studium:

1981-1987 Georg-August-Universität Göttingen

Approbation: 
11.12.1987

Promotion: 
08.11.1988; Thema: Wachstum und Differenzierung embryonaler Hühner- Retina in der Zellkultur: Der Einfluss der Neuron-Glia Interaktion auf die Entwicklung der Zytoarchitektur.

Ausbildung: 
Neurochirurgischen Klinik Göttingen 1988 - 1997

Facharztanerkennung: 
11.06.1997

Habilitation: 
11.06.2001; Thema: Die Expression der Stickstoffoxid generierenden Isoenzyme in Astrozytomen (WHO Grad I-III) und Glioblastomen und die Modulation von Proliferation, Migration und Tumorprogression.

Apl. Professur: 

06.06.2008

Schwerpunkte

Klinische Schwerpunkte:

Pädiatrische Neurochirurgie, Intensivmedizin, Multimodales Neuromonitoring.

Wissenschaftliche Schwerpunkte: 

Laser-assistierte Neuroendoskopie, Hydrozephalus

Publikationen

Rohde V, Behm T, Ludwig H, Wachter D: The role of neuronavigation in intracranial endoscopic procedures. Neurosurg Rev (epub first)

Ludwig HC: Notfälle bei Kindern mit Liquorshunt-Systemen. Kinderärztliche Praxis 6; 2010

Sprung C, Schlosser HG, Lemcke J, Meier U, Messing-Junger M, Trost HA, Weber F, Schul C, Rohde V, Ludwig HC, Hopfner J, Sepehrnia A, Mirzayan MJ, Krauss JK: The adjustable proGAV shunt: a prospective safety and reliability multicenter study. Neurosurgery 2010; 66(3):465-474 Lemcke J, Meier U, Muller C, Fritsch M, Eymann R, Kiefer M, Kehler U, Langer N, Rohde V, Ludwig HC, Weber F, Remenez V, Schuhmann M, Stengel D: Is it possible to minimize overdrainage complications with gravitational units in patients with idiopathic normal pressure hydrocephalus? Protocol of the randomized controlled SVASONA Trial (ISRCTN51046698). Acta Neurochir (Suppl) 2010; 106:113-115

Rohde V, Haberl H, Ludwig H, Thomale UW: First experiences with an adjustable gravitational valve in childhood hydrocephalus. J Neurosurg Pediatrics 3:81-89, 2009

Gutenberg A, Schulten HJ, Gunawan B, Ludwig HC, Bruck W, Larsen J, Rohde V: CNS tumor 22 years after spinal neuroblastoma IV: diagnostic dilemma between recurrence and secondary malignancy. Pediatr Neurosurg 2009; 45(1):61-68

Ludwig HC, Kruschat T, Knobloch T, Teichmann HO, Rostasy K, Rohde V: First experiences with a 2.0-mum near infrared laser system for neuroendoscopy. Neurosurg Rev 30:195-201, 2007

Stettner GM, Rostasy KM, Ludwig HC, Merkler D, Fahsold R, Gartner J: Infratentorial meningioma in an 8-year-old child as first sign of neurofibromatosis type 2. Neuropediatrics. 2007 Feb;38(1):29-31.

Ludwig HC: Die aktuelle Therapie des Hydrozephalus: Shunt oder laserassistierte Neuroendoskopie? Pädiatrie hautnah 3: 156-162; 2007

Schaller B, Kruschat T, Schmidt H, Bruck W, Buchfelder M, Ludwig HC: Intradural, extramedullary spinal sarcoidosis: report of a rare case and review of the literature. Spine J 2006; 6(2):204-210

Kramer FJ, Ludwig HC, Materna T, Gruber R, Merten HA, Schliephake H: Piezoelectric osteotomies in craniofacial procedures: a series of 15 pediatric patients. Technical note. J Neurosurg 2006; 104(1 Suppl):68-71

Diedrich A, Bock HC, Konig F, Schulz TG, Ludwig HC, Herken R, Quondamatteo F: Expression of glutathione S-transferase T1 (GSTT1) in human brain tumours. Histol Histopathol 21:1199-1207, 2006

Ludwig HC, Kruschat T, Knobloch T, Rostasy K, Buchfelder M: Endoscopic cystoventriculostomy and ventriculocysternostomy using a recently developed 2.0-micron fiber-guided high-power diode-pumped solid state laser in children with hydrocephalus. Proc SPIE Int Soc Opt Eng 25;5686(1):558-65; 2005

Schaller BJ, Gruber R, Merten HA, Kruschat T, Schliephake H, Buchfelder M, Ludwig HC: Piezoelectric bone surgery: a revolutionary technique for minimally invasive surgery in cranial base and spinal surgery? Technical note. Neurosurgery 2005; 57(4 Suppl):E410

Ludwig HC: Die Verhandlungsfähigkeit neurochirurgischer Patienten. Rechtsmedizin 15:138-140; 2005

Verheggen R, Ludwig HC, Merten HA: Experiences with Lactosorb miniplates and screws - long-term follow-up data in paediatric patients and infant minipigs. Osteol 14:101-110; 2005

Gutenberg A, Brück W, Buchfelder M, Ludwig HC: Expression of tyrosine kinases FAK and Pyk2 in 331 human astrocytomas. Acta Neuropathol (Berlin) 108: 224-230, 2004

Rostasy KM, Sponholz S, Bahn E, Ludwig HC, Hanefeld V: Unusual localization of a choroid plexus papilloma in a 4-year-old female. Pediatric Neurology 28: 66-68, 2003

Honig JF, Merten HA, Ludwig HC, Behnke-Mursch J: Subgaleal versus subperiostal dissection in fronto-orbital advancement procedures. J Craniofac Surg 12: 287-91, 2001

Ludwig HC, Feiz-Erfan I, Bockermann V, Behnke-Mursch J, Schallock K, Markakis E: Expression of nitric oxide synthase isozymes (NOS I-III) by immunhistochemistry and DNA in situ hybridization. Correlation with macrophage presence, vascular endothelial growth factor (VEGF) and oedema volumetric data in 220 glioblastomas. Anticancer Res 20: 299-304; 2000

Ludwig HC, Akhavan-Sigari R, Rausch S, Schallock K, Quentin C, Ziegler D, Bockermann V, Markakis E: Oedema extension in cerebral metastasis and correlation with the expression of nitric oxide synthase isozymes (NOS I-III). Anticancer Res 20: 305-310; 2000

Ludwig HC, Klingler M, Timmermann A, Weyland W, Mursch K, Reparon C, Markakis E: The influence of airway pressure changes on intracranial pressure (ICP) and the blood flow velocity in the middle cerebral artery (VMCA). Anästhesiol Intensivmed Notfallmed Schmerzther 35: 141-145, 2000

Ludwig HC, Akhavan-Sigari R, Rausch S, Schallock K, Quentin C, Bockermann V, Kolenda H: Expression of fokal adhesion kinase (p125 FAK) and proline-rich tyrosine kinase 2 (PYK2/CAK ) in cerebral metastases, correlation with VEGF-R-, ecNOS III-labelling and morphometric data. Anticancer Res 20: 1419-1424, 2000

Weyland A, Buhre W, Grund S, Ludwig HC, Kazmaier S, Weyland W, Sonntag H: Cerebrovascular tone rather than intracranial pressure determines the effective downstream pressure of the cerebral circulation in the absence of intracranial pressure. J Neurosurg Anesthesiol 12: 210-216, 2000

Birbilis TH, Ludwig HC, Markakis E: Neuropathy of the sural nerve caused by external pressure. Acta Neurochir (Wien) 142:951-952, 2000

Lang JK, Ludwig HC, Mursch K, Zimmerer B, Markakis E: Elevated cerebral perfusion pressure and low colloid osmotic pressure as a risk factor for subdural space-occupying hygromas ? Surg Neurol 52:630-637; 1999

Ludwig HC, Rausch S, Schallock K, Markakis E: Expression of CD 73 (ecto-5`-nucleotidase) in 165 glioblastomas. Anticancer Res 19: 1747-52; 1999

Ludwig HC, Behnke J, Markakis E: Brain metastases in neurosurgery: indications, surgical procedures and outcome. Anticancer Research 18:2215-2218; 1998

Mursch K, Ludwig HC, Behnke-Mursch J, Markakis E: Symptomatische Trigeminusneuralgie als Symptom einer infratentoriellen Raumforderung: Schmerz. 11:263-267; 1997

Mursch K, Vogelsang JP, Zimmerer B, Ludwig HC, Behnke J, Markakis E: Bedside measurement of the third ventricle`s diameter during episodes of rising intracranial pressure after head trauma. Acta Neurochir (Wien) 137: 19-24; 1995

Ludwig HC, Bauer C, Behnke J, Fuhrberg P, Teichmann HP, Markakis E: Immunhistochemical and electronmicroscopic effects of a new 2.09 µm Ho:YAG laser on the rat brain. Ann Acad Med Singapore 23: 21-26; 1994

Mursch K, Vogelsang JP, Zimmerer B, Ludwig HC, Behnke J, Markakis E: Bedside measurement of the third ventricle`s diameter during episodes of rising intracranial pressure after head trauma. Acta Neurochir (Wien) 137: 19-24; 1995

Koch A, Hollmann K, Undt G, Ludwig HC, Verheggen R: Die Rekonstruktion des Orbitadaches nach Tumorresektion mit einem muskelgestielten Kalottendeckel - der Calvaria-temporalis-Lappen. Fortschr Kiefer Gesichts Chir 39: 50-52; 1994

The European Study Group On Nimodipine In Severe Head Injury: A multicenter trial of the efficacy of nimodipine on outcome after severe head injury. J Neurosurg 80:797-804; 1994

Verheggen R, Schrör K, Ludwig HC, Spoerri PE: Results of various methods to investigate the function of postmortem human and bovine basilar arteries. Neurosurg Rev 14: 37-42; 1991

Spoerri PE, Ulshafer RJ, Ludwig HC, Allen CB, Kelley KC: Photoreceptor cell development in vitro: influence of pigment epithelium conditioned medium on outer segment differentiation. Eur J Cell Biol 46: 362-367; 1988

Spoerri PE, Ludwig HC, Ogawa Y: A modified silver method for demonstrating developing nervous tissue in culture. Acta Anat 123: 64-66; 1985

 

Neurochirurgie Göttingen

Die Neurochirurgische Klinik der Universitätsmedizin ist mit 5.000 ambulanten und 2.000 stationären Patienten sowie 3.000 Operationen pro Jahr eine der größten neurochirurgischen Kliniken Deutschlands.

Kontakt

Universitätsklinikum Göttingen
Neurochirurgische Klinik
Robert-Koch-Strasse 40
37075 Göttingen

Tel. 0551 39-66033

Fax 0551 39-8794

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